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Lankester was back in Costa Rica in 1922 asthma kids mild intermittent order 500 mcg advair diskus otc, the year that was a turning point in his career as an orchidologist: it brought the first correspondence with Oakes Ames asthmatic bronchitis 4 months order advair diskus 100mcg amex. In 1922 asthma definition quadrilateral buy discount advair diskus 250mcg, Ames began a series of publications on orchids, which he named Schedulae Orchidianae. In its third fascicle, in January 1923, Ames started to describe many of the Lankester orchids, which were deposited at Kew and had been left unidentified. Ames was taken in more by administrative work at Harvard, and Lankester traveled abroad more frequently. Irish coast) left Southampton with myself on board en route for Costa Rica, and here I am still. Endrйs (1838-1874), Alberto Manuel Brenes (1870-1948) and Charles Herbert Lankester (1879-1969). His orchid collections, with over 3,500 numbers, form an important part of the Reichenbach orchid herbarium at the Vienna Natural History Museum. Central Valley, did little botanical work but made extraordinary collections of orchids in the surrounding mountains. These include dozens of new species, described by Rudolf Schlechter in his Additamenta ad Orchideologiam Costaricensem (1923) in a chapter entitled Orchidaceae Brenesianae. He lost both parents when only three years old and was raised, together with his sister, by two aunts. It was in London that he read an announcement in the Daily Telegraph, offering a position in Costa Rica to a young Englishman willing to work as an assistant to the recently founded Sarapiquн Coffee Estates Company. Lankester applied and was hired, landing a few months later in Puerto Limуn, then going on by train to the capital of Costa Rica, where he arrived just in time to take part in the "Ball of the New Century", given by the president of Costa Rica, Rafael Yglesias, in the National Theater, San Josй. It was here, surrounded by the most exuberant tropical vegetation, that his interests in plants, insects and birds began. Louis Williams wrote in his obituary, "Don Carlos Lankester arrived at the right place at the right time to join into the active biological exploration of Costa Rica, perhaps the most exciting place biologically on our continent. Lankester, his life and legacy 361 Director of the Natural History Museum in London. The arrival of these academics marks the beginning of a small scientific awakening in Costa Rica. Among the teachers hired were Pablo Biolley (1861-1908) and Henri Francois Pittier (1857-1950). Pittier lived in Costa Rica until 1905 and spent some of this time conducting a systematic exploration of the Costa Rican flora; a study that had no equal in any country of tropical America at that time. Again citing Standley, in 1903 the National Herbarium "was unequaled below the Rнo Grande del Norte (Standley, 1937:50). The other players in this scientific awakening, Alfaro, Biolley, Tonduz, Wercklй, the Brades, and, years later, Otуn Jimйnez would also be important to Lankester, as they often accompanied him on his collecting excursions and were frequent visitors to his farm in Cartago. Lankester was thus forced to work with different companies until 1908, when he left for England to marry Dorothea Mary Hawker. It was not a typical Costa Rica residence, for although built of adobe it was two-storied and had no patio. However, living in Cachн, at that time one of the regions with the greatest botanical diversity, he must have fallen under the spell of the plant world as he soon began collecting orchids in the nearby woods. The first mention of orchids in his correspondence is in a letter to Hill of December 1910, where he wrote: "I have a few orchids chiefly of botanical interest, which I will send when it gets warmer on your side". At the same time, Lankester began his collection of living plants that would become so famous years later. Lankester returned to England in 1920 to enroll his five children (four daughters and one son) in English schools. When Lankester returned to England, he found that Rolfe had died the year before, just as he was preparing to travel to Costa Rica and Panama on his first field trip to tropical America. Lankester was back in Costa Rica in 1922, the year that was a turning point in his career as an orchidologist: it brought the first correspondence with Oakes Ames (1874-1950) - the start of a deep and long-lasting friendship. To understand what was happening in the world of orchidology, it must be remembered that up to the 1920s, the study and knowledge of orchids was strictly an European business.

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Short-acting sulfonamides (sulfanilamide asthma jaw pain safe advair diskus 100mcg, sulfamerazine asthma treatment guidelines 2016 generic advair diskus 500mcg without a prescription, sulfacetamide asthma definition 2 buy advair diskus 100mcg amex, sulfixazole, sulfadimidine, sulfamethizole) 2. Sulfonamides are mainly bacteriostatic but in very high concentration they may act as bactericidal. They are effective against a number of gramnegative and gram-positive organisms and certain chlamydia, nocardia, actinomyces and toxoplasma infections. A variety of microorganisms, Pseudomonas pyocyanea, Corynebacterium diphtheriae, Salmonella and Mycobacterium tuberculosis and anaerobic Streptococci, are not sensitive to sulfonamides. A severe exudative type of erythema associated with widespread lesions of skin and mucous membrane (Stevens-Johnson syndrome) has been noticed with long-acting sulfonamide therapy. Aqueous soluble sodium sulfacetamide (10%, 20%, or 30%) in drops or as ointment (6%) is used in conjunctival or corneal infections. Systemic administration of sulfonamides gives high concentration in the aqueous as they are lipid soluble and pass the blood-aqueous barrier easily. Short-acting sulfonamides are administered in an average dose of 2 g initially followed by a sixhourly maintenance dose of 1 g. In children, the daily doses should be calculated on the basis of 150 mg/kg body weight, and be given in divided doses. In case of long-acting sulfonamides, an initial dose of 1 g is given and is followed by 0. Trimethoprim-Sulfamethoxazole (Cotrimoxazole) the introduction of trimethoprim with sulfamethoxazole is considered as an important advancement in chemotherapy. The antibacterial spectrum of trimethoprim is similar to that of sulfamethoxazole, but the former is usually 20 to 100 times more potent than the latter. The combination acts on two steps of enzymatic pathway for the synthesis of tetrahydrofolic acid. Further, trimethoprim is a highly selective inhibitor of dihydrofolate reductase of lower organisms. Cotrimoxazole is available in oral tablets containing 80 mg of trimethoprim and 400 mg of sulfamethoxazole. The usual adult dose is 2 tablets every twelve hours for 10 to 14 days for management of most of the ocular infections. The combination should be used with caution in children under twelve years of age and pregnant women. Antibiotics Antibiotics are substances obtained from microorganisms that in high dilution can inhibit the growth of other microorganisms. Majority of antibiotics are derived from fungi but some like bacitracin, polymyxin B and colistin are obtained from bacteria. Antibiotics have a selective action on microorganisms, some affect primarily gram-positive bacteria, others inhibit gramnegative bacteria and still others inhibit only certain fungi, yeast or protozoa. Those inhibiting only one group of microorganisms are called narrow-spectrum antibiotics, while those inhibiting 94 Textbook of Ophthalmology both gram-positive and gram- negative bacteria, rickettsiae and chlamydia are termed broadspectrum antibiotics. Penicillin, a beta-lactam antibiotic, is widely used in the control of infection because of its wide range of bactericidal action. It is effective against cocci and gram-positive organisms, but gram-negative bacilli are relatively insensitive. Penicillin may be administered locally in the form of drops (5000 to 10000 units/ml), ointment (2000 units/g), powder or as subconjunctival injection. Drops should be instilled into the eye frequently (hourly or two hourly) to control acute conjunctivitis. Systemic administration of penicillin produces effective concentration in the tissues. Benzyl penicillin injection (500,000 units intramuscular eight hourly) or benzyl penicillin tablets (50000 to 500,000 units four hourly) produce therapeutic levels in the plasma. The drug is quite safe but some individuals are so sensitive to it Mechanisms of Action and Classification There are several ways to classify antibiotic agents, however, the most common classification is based on their mode of action.

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We also thank Wesley Higgins for commenting on the manuscript asthma jams vine purchase advair diskus 500mcg on-line, Steve Beckendorf asthma symptoms heart palpitations advair diskus 100mcg with amex, Guido and Karel Deburghgraeve for stimulating company in the field asthma definition lungs order 100 mcg advair diskus free shipping, and Manolo Arias together with his staff and family in Lima for gracious logistic support. New combinations in Odontoglossum (Orchidaceae: Oncidiinae) and a solution to a taxonomic conundrum. A new species of Odontoglossum with an extraordinary long column and filamentose lip callus is described, illustrated with a photograph and a line drawing, and compared with similar and presumably closely related species, such as O. The new species belongs to the Odontoglossum complex with a flexible lip-base attachment, but differs from all other species in that complex primarily by the elongate base of the column, below the attachment of the strap-like lip-base. Years ago, when the wilds of Columbia were more untrodden than they are now, we found less difficulty, but year by year such prizes get rarer. The time is not far distant when home skill in hybridization will have to supply novelties in Odontoglossums. Even today experienced "orchid hunters" seem to think that there is not much more to discover when it comes to this attractive genus. But this has been proven to be a hasty conclusion thanks to the discovery of several new species in later years (Dalstrцm 1993, 1996, 1999, 2010, 2012b, 2013) although in honesty, it must be said that Odontoglossum taxonomy needs some special effort to be understood properly. This transfer may well have been allowed by molecular analysis but the argument that few people can separate an Odontoglossum from an Oncidium Sw. The first author of the present paper has outlined an alternative taxonomic treatment (Dalstrцm 2012a), which explains why keeping a slightly enlarged genus Odontoglossum is preferable, and also how to separate this genus from Oncidium based on a combination of morphological, ecological and geographical characteristics. Another argument that has been heard in the debate about how to best treat these orchids is that many new names have to be created for various smaller groups of plants if we want to keep Odontoglossum as a valid genus. Some of the species in the chrysomorphum clade also produce aborted flowers occasionally, in addition to displaying morphological similarities in the pollination apparatus (column, rostellum and pollinarium shapes primarily) to species in the Heteranthocidium complex. Plants in the boothianum clade also show similar intermediate features and only marginally differ from the chrysomorphum clade. The fact that these two smaller groups occur one after the other near the base of the Odontoglossum clade may perhaps be the result from several occasions of ancient natural hybridization. These speculations, however, should not be taken for anything other than just that at this time, but rather than to close the door (and settle the debate) to a deeper understanding of the evolution of these orchids, they should be seen as encouragements to further studies. Although many Odontoglossum species may appear superficially similar, the one described here does not need any particular effort to be recognized as new and different. It is characterized by a unique combination of morphologic features such as the elongated column together with the extremely long and irregularly filamentose callus teeth on the lip, which readily set it apart from its closest relatives; O. Pasco: Exact locality unknown but recent observations suggest that the true origin is somewhere near the town of Oxapampa. Leaves subpetiolate, conduplicate, elongate elliptic to obovate, narrowly acute to shortly acuminate, 19­27 Ч 2. Inflorescences 1 to 3, axillary from the base of the uppermost sheaths, arching to subpendent, loosely flowered, flexuous, few to many flowered racemes or loosely paniculate with few basal fewflowered side-branches, to ca. Flower stellate to slightly campanulate and rather arachnoid; dorsal sepal yellow almost covered with large brown spots, subunguiculate, elliptic to ovate, acuminate, ca. The type plant was originally imported to Europe as "Odontoglossum epidendroides", or possibly "O. The original identification was probably based on similarities to then known Odontoglossum species. A new Bolivian species of Odontoglossum (Orchidaceae; Oncidiinae) in the astranthum complex. A well-known but previously misidentified Odontoglossum (Orchidaceae: Oncidiinae) from Ecuador. Eine neues, seltsames Odontoglossum as dem Astranthum-Komplex (Orchidaceae: Oncidiinae) der Amazonas-Region in Peru. The authors thank Wesley Higgins for commenting on the manuscript, Guido Deburghgraeve for cultivating the type plant, and Manolo Arias together with his staff and family in Lima for gracious logistic support. Contemporary patterns of plant biodiversity result from the ecological and evolutionary processes generated by species interactions. Understanding these interactions is key for effective biodiversity conservation at the species and the ecosystem level. Orchid species often have highly specialised pollinator interactions, and the preservation of these is critical for in situ orchid conservation. The majority of orchid species occur in tropical regions, and information regarding their interactions is limited.

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